Day hotels available in Otay Mesa: 26Sort by:PopularityPorto Vista Hotel In Little ItalyPreviousNextPool access includedPorto Vista Hotel In Little ItalyLittle Italy4.2/5 | 30 ReviewsFree cancellationPayment at the hotelUS$89-51%US$180 per nightPrevious8am - 2pm10am - 5pm3pm - 11pmNextDays Inn by Wyndham San Diego/Downtown/Convention CenterPreviousNextDays Inn by Wyndham San Diego/Downtown/Convention CenterCore-Columbia4.1/5 | 28 ReviewsFree cancellationPayment at the hotelUS$75-61%US$189 per nightPrevious9am - 4pmNextThe Guild Hotel, San Diego, A Tribute Portfolio Hotel by MarriottPreviousNextThe Guild Hotel, San Diego, A Tribute Portfolio Hotel by MarriottCore-Columbia4.3/5 | 5 ReviewsFree cancellationPayment at the hotelUS$129-36%US$200 per nightPrevious8am - 2pm10am - 5pmNextMargaritaville Hotel San Diego Gaslamp QuarterPreviousNextPool access includedMargaritaville Hotel San Diego Gaslamp QuarterEast Village4.9/5 | 21 ReviewsFree cancellationPayment at the hotelUS$99-67%US$299 per nightPrevious9am - 5pm4pm - 11pmNextMotel 6-San Diego, CA - DowntownPreviousNextMotel 6-San Diego, CA - DowntownCoronado3.8/5 | 2 ReviewsFree cancellationPayment at the hotelUS$60-34%US$90 per nightPrevious8am - 2pm9am - 4pm1pm - 7pm5pm - 10pmNextManchester Grand Hyatt San DiegoPreviousNextPool access includedManchester Grand Hyatt San DiegoMarina4.7/5 | 30 ReviewsFree cancellationPayment at the hotelUS$220-38%US$350 per nightPrevious9am - 5pm11am - 6pmNextBaymont by Wyndham San Diego DowntownPreviousNextBaymont by Wyndham San Diego DowntownCore-Columbia4.1/5 | 6 ReviewsFree cancellationPayment at the hotelUS$75-56%US$169 per nightPrevious10am - 4pmNextThe Bristol Hotel San DiegoPreviousNextThe Bristol Hotel San DiegoCore-Columbia4.7/5 | 7 ReviewsFree cancellationPayment at the hotelUS$99-29%US$139 per nightPrevious7am - 1pmNextResidence Inn by Marriott San Diego DowntownPreviousNextPool access includedResidence Inn by Marriott San Diego DowntownLittle Italy4.6/5 | 10 ReviewsFree cancellationPayment at the hotelUS$150-35%US$229 per nightPrevious10am - 5pmNextCourtyard by Marriott San Diego DowntownPreviousNextCourtyard by Marriott San Diego DowntownCore-Columbia4.8/5 | 13 ReviewsFree cancellationPayment at the hotelUS$179-17%US$215 per nightPrevious7am - 6pm9am - 4pm10am - 6pmNextHampton Inn San Diego-DowntownPreviousNextPool access includedHampton Inn San Diego-DowntownSan Diego, CA4.6/5 | 2 ReviewsFree cancellationPayment at the hotelUS$145-52%US$299 per nightPrevious10am - 4pmNextBest Western San Diego Zoo/SeaWorld Inn & SuitesPreviousNextPool access includedBest Western San Diego Zoo/SeaWorld Inn & SuitesMission Valley4.5/5 | 71 ReviewsFree cancellationPayment at the hotelUS$80-56%US$179 per nightPrevious7am - 6pm3pm - 9pmNextHotel Iris - Mission Valley-San Diego Zoo-SeaWorldPreviousNextPool access includedHotel Iris - Mission Valley-San Diego Zoo-SeaWorldMission Valley3.6/5 | 17 ReviewsFree cancellationPayment at the hotelUS$75-32%US$109 per nightPrevious10am - 3:30pmNextEmbassy Suites by Hilton San Diego - La JollaPreviousNextPool access includedEmbassy Suites by Hilton San Diego - La JollaSan Diego, CA4.7/5 | 8 ReviewsFree cancellationPayment at the hotelUS$149-49%US$289 per nightPrevious10am - 4pmNextMission View Inn & Suites San Diego Sea World - ZooPreviousNextPool access includedMission View Inn & Suites San Diego Sea World - ZooMission Valley4.1/5 | 11 ReviewsFree cancellationPayment at the hotelUS$89-56%US$199 per nightPrevious9am - 3pm10am - 3pmNextComfort Inn San Diego Airport At The HarborPreviousNextPool access includedComfort Inn San Diego Airport At The HarborSan Diego, CA4.1/5 | 10 ReviewsFree cancellationPayment at the hotelUS$89-32%US$129 per nightPrevious10am - 4pm11am - 5pmNextHoliday Inn Express & Suites San Diego - Mission Valley, an IHG HotelPreviousNextPool access includedHoliday Inn Express & Suites San Diego - Mission Valley, an IHG HotelMission ValleyFree cancellationPayment at the hotelUS$100-45%US$180 per nightPrevious10am - 3pmNextEmpress Hotel La JollaPreviousNextEmpress Hotel La JollaLa Jolla4.8/5 | 6 ReviewsFree cancellationPayment at the hotelUS$99-58%US$235 per nightPrevious8am - 1pm10am - 4pmNextLa Jolla Cove Hotel & SuitesPreviousNextPool access includedLa Jolla Cove Hotel & SuitesLa Jolla3.9/5 | 12 ReviewsFree cancellationPayment at the hotelUS$109-58%US$259 per nightPrevious10am - 5pm1pm - 7pmNextThe Westin San Diego BayviewPreviousNextPool access includedThe Westin San Diego BayviewCore-Columbia4.7/5 | 29 ReviewsFree cancellationPayment at the hotelSold out offersKimpton Hotel Palomar San DiegoPreviousNextPool access includedKimpton Hotel Palomar San DiegoCore-Columbia4.8/5 | 7 ReviewsFree cancellationPayment at the hotelSold out offersThe El Cordova HotelPreviousNextPool access includedThe El Cordova HotelCoronadoFree cancellationPayment at the hotelSold out offersRamada by Wyndham San Diego National CityPreviousNextPool access includedRamada by Wyndham San Diego National CityNational City4.1/5 | 12 ReviewsFree cancellationPayment at the hotelSold out offersOld Town Western InnPreviousNextOld Town Western InnOld TownFree cancellationPayment at the hotelSold out offersDoubleTree By Hilton San Diego Hotel CirclePreviousNextPool access includedDoubleTree By Hilton San Diego Hotel CircleSan Diego, CA4.3/5 | 6 ReviewsFree cancellationPayment at the hotelSold out offersHyatt Regency Mission Bay Spa & MarinaPreviousNextPool access includedHyatt Regency Mission Bay Spa & MarinaMission Bay5/5 | 3 ReviewsFree cancellationPayment at the hotelSold out offers1