MERCURE FRA APT NEU ISENBURG4*. Take line A661, station Neu-Isenburg, direction Neu-Isenburg. The Mercure Hotel Frankfurt Airport Neu-Isenburg is just a few minutes from the airport. Easily accessible from the nearby Isenburg Zentrum Süd bus stop or the Neu-Isenburg exit from the A3 highway, and approximately 1.2 miles from the train station. Arou nd 15 minutes from Frankfurt city center and the exhibition center. Shop at the nearby "Isenburg Zentrum" shopping center in Neu-Isenburg. The Commerzbank Arena is just 1.6 miles from the hotel.